BPC-157 / TB-500
Dual-peptide formulation for tissue repair, cell migration, and angiogenic research

An optimized research blend combining the tissue-healing properties of the pentadecapeptide BPC-157 with the systemic cell-migration actions of the Thymosin Beta-4 fragment TB-500. This compound is heavily studied in preclinical models for its synergistic potential in accelerating musculoskeletal, ligament, and gastrointestinal tissue repair.
- Typical dose
- 300 - 500 mcg per peptide administered daily or every other day in animal models (subject to weight-based scaling)
- Half-life
- BPC-157: ~4 hours (estimated); TB-500: ~24-36 hours
- Administration
- Subcutaneous or Intramuscular Injection (for laboratory research models)
- Research status
- Preclinical / Research Use Only
What it is
The BPC/TB blend combines BPC-157 with TB-500 (thymosin beta-4 fragment). Together they promote angiogenesis, tissue remodeling, and inflammation control — earning the nickname 'Wolverine Blend' for its healing reputation.
Why researchers use it
- BPC-157 encourages new blood-vessel formation and supports tendon, ligament, and gut healing
- TB-500 enhances cell migration and cytoskeletal repair, accelerating tissue recovery
- Combined effect reduces inflammation while accelerating repair and resilience
Dosing protocol (for research)
Reconstitution (single 20 mg vial):
- 10 mg BPC-157 + 10 mg TB-500 with 2 mL BAC water
- Final concentration: 5 mg/mL of each peptide
- Each 0.1 mL (10 units) = 500 mcg BPC-157 + 500 mcg TB-500
Typical use: 0.1–0.2 mL daily delivering both compounds proportionally
Duration: acute injury 4–6 weeks; general recovery 2–4 weeks
Preparation & injection
- Swirl to dissolve, do not shake
- Store refrigerated, away from light
- Subcutaneous injection, near injury site when appropriate; rotate SubQ sites otherwise
Safety notes
- Generally well-tolerated in early studies
- Possible mild effects: redness at injection site, headache, or fatigue
- Purity and sterility are critical
Researcher tips
- Injecting closer to injury sites is often preferred for localized repair
- Sometimes paired with GHK-Cu or physical therapy for enhanced results
- Keep precise logs of dosing, timing, and physical outcomes
Reconstitution & concentration
Single vial contains 10 mg BPC-157 + 10 mg TB-500 (20 mg total).
- Reconstitute with 2 mL bacteriostatic water
- Final concentration: 5 mg/mL of each peptide
- Each 0.1 mL (10 units) = 500 mcg BPC-157 + 500 mcg TB-500
Common research dosing: BPC-157 200–750 mcg up to twice daily; TB-500 ~3 mg every other day. As a blend, researchers align daily injections so each 0.1–0.2 mL delivers both compounds proportionally. Duration: 4–6 weeks for acute injury; 2–4 weeks for general recovery.
Stacks
The Wolverine Blend — the gold-standard research combo for musculoskeletal and tendon healing. It's described rapid joint, tendon, and soft-tissue recovery, often cycled for 4–6 weeks. SubQ near the injury site is preferred where possible.
For specialized recovery timing, protocols recommend consistent daily dosing at the same time for stable serum levels.
Where to source
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